Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Weston, B.W.; Nair, R.P.; Larsen, R.D.; Lowe, J.B.
    Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities (1992), J. Biol. Chem., 267, 4152-4160.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.65 expression in COS cells Homo sapiens
2.4.1.152 expression in COS cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.152 membrane type II membrane protein, membrane-bound form in trans cistermae of Golgi Homo sapiens 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.152 43008
-
 1 * 43008, calculation from nucleotide sequence Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.65 Homo sapiens
-
-
-
2.4.1.152 Homo sapiens Q11128
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.152 leukocyte
-
 Homo sapiens
-
2.4.1.152 peripheral blood
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.65 GDP-L-fucose + 2'-fucosyllactose 254% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + ?
-
 ?
2.4.1.65 GDP-L-fucose + alpha(2,3)-sialyllactosamine 56% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + ?
-
 ?
2.4.1.65 GDP-L-fucose + Galbeta(1,3)GlcNAc 420% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + Galbeta(1,3)(Fucalpha(1,4))GlcNAc
-
 ?
2.4.1.65 GDP-L-fucose + Galbeta(1,4)Glc 145% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + Galbeta(1,4)(Fucalpha(1,3))Glc
-
 ?
2.4.1.152 GDP-L-fucose + 2'-fucosyllactose 42% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + ?
-
 ?
2.4.1.152 GDP-L-fucose + alpha(2,3)sialyllactosamine
-
 Homo sapiens GDP + ?
-
 ?
2.4.1.152 GDP-L-fucose + Fucalpha(1,2)Galbeta(1,4)Glc
-
 Homo sapiens GDP + Fucalpha(1,2)Galbeta(1,4)(Fucalpha(1,3))Glc
-
 ?
2.4.1.152 GDP-L-fucose + Galbeta(1,3)GlcNAc i.e. lacto-N-biose I, 10% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + ?
-
 ?
2.4.1.152 GDP-L-fucose + Galbeta(1,4)GlcNAc
-
 Homo sapiens GDP + Galbeta(1,4)(Fucalpha(1,3))GlcNAc
-
 ?
2.4.1.152 GDP-L-fucose + Galbeta(1,4)GlcNAc i.e. N-acetyllactosamine Homo sapiens GDP + Galbeta(1,4)(Fucalpha(1,3))GlcNAc
-
 ?
2.4.1.152 GDP-L-fucose + lacto-N-biose I
-
 Homo sapiens GDP + ?
-
 ?
2.4.1.152 GDP-L-fucose + lactose 11% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.1.152 monomer 1 * 43008, calculation from nucleotide sequence Homo sapiens